The Future Of Venture Capital: Where The Smart Money Will Flow In Half A Decade

where vcs will be investing in 5 years

In five years, venture capital (VC) investors will continue to be cautious, but there are several areas that are already showing signs of VC interest. These include sustainability, healthcare, fintech, and diversity and inclusion.

Sustainability and clean energy are expected to attract more VC investment due to growing concerns about climate change. Healthcare will likely remain a significant area of investment because of ageing populations and the ongoing pandemic. The rise of cryptocurrencies and blockchain technology will also probably lead to more VC funding in fintech. Additionally, with the increasing focus on diversity and inclusion in the workplace, companies promoting these values are expected to receive more investment.

VC investment has been successful over the last decade, with an average net return of 14.5% per year. However, it is important to note that VC investments are unlike traditional forms of financial investing and have consistently underperformed relative to public markets and other alternative assets.

Characteristics Values
Generative AI Will continue to streamline workflows and drive efficiencies
Dry powder $317 billion in reserves
Sustainable start-ups Gaining momentum
IPO activity Expected to resurge
Technology Software, fintech, artificial intelligence, and cybersecurity
Healthcare Biotech, medical devices, and digital health
Consumer E-commerce, food and beverage, and fashion

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Technology

Artificial Intelligence (AI) and Machine Learning

AI and machine learning have been gaining traction among VCs, with Forbes' 2024 Midas List highlighting the rise of AI startup valuations. OpenAI, the maker of ChatGPT, has boosted investor Alfred Lin back to the top spot on the Midas List. Other AI standouts, such as Anthropic and Cohere, have also attracted VC investments. The AI sector is expected to continue its rapid growth, creating opportunities for VCs.

Software as a Service (SaaS)

SaaS is becoming an increasingly profitable route for VCs, as it helps optimize business processes and enables more fluid and automated operations. Notable VC firms investing in SaaS include Sequoia Capital, The SaaStr Fund, Andreessen Horowitz, and Costanoa Ventures. These firms are backing a range of SaaS startups, such as Mixmax, Automile, and Teamable.

Cybersecurity

With the increasing importance of data protection and online security, VCs are paying close attention to the cybersecurity sector. Shah, a general partner at Index Ventures, has made notable investments in cybersecurity deals, including Coalition, Datadog, and Wiz. Cybersecurity deals offer attractive opportunities for VCs looking to invest in technology.

Climate Tech and Sustainability

Climate tech and sustainability are attracting significant VC investments, with an $8.1 billion start to funding in 2024. VCs are recognizing the importance of reducing CO2 emissions and promoting sustainable practices. This trend is expected to continue, with increasing regulatory pressure and consumer demand for environmentally friendly solutions.

Manufacturing and Supply Chain

The manufacturing and supply chain sectors are undergoing digital transformation, and VCs are taking note. Eclipse Ventures, for example, has identified significant opportunities for innovation in these sectors due to the vulnerabilities exposed by the COVID-19 pandemic. VCs are investing in digital solutions that offer manufacturers greater agility and resilience, as well as supply chain visibility and efficiency.

Consumer Hardware

While consumer hardware has always been a challenging market, VCs are still investing in this sector. The COVID-19 pandemic has created opportunities for at-home fitness startups, such as Peloton, Tonal, and Mirror. VCs are also interested in companies that can offer differentiated experiences, social interactions, and gamification to drive growth.

These are just a few examples of the technology sectors that VCs are likely to focus on in the next five years. It's important to note that VC investment trends can change rapidly, and new technologies or sectors may emerge that attract significant attention.

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Healthcare

Venture capital (VC) firms have been instrumental in driving innovation and growth in the healthcare industry. Despite a projected industry-wide slowdown in VC investments in 2023, the healthcare sector is expected to remain a key focus area for VCs over the next five years. Here are some key areas within healthcare that are likely to attract VC investments during this period:

Biopharma

Investment in the biopharma sector is expected to remain robust, with a focus on autoimmune and respiratory companies. While investment in this sector may not reach the record highs of 2021 ($38.7 billion), it is still expected to maintain healthy levels, with a projected investment of around $27.4 billion in 2023.

Medical Devices

The medical devices sector is another key area of interest for VCs. This sector includes companies developing innovative medical technologies and devices that enhance patient care, improve treatment outcomes, and streamline healthcare delivery. While investments may mirror the 2020 levels of $6.6 billion, there will likely be a decrease in the number of $100+ million deals.

Medical Diagnostics

VC investment in medical diagnostics and tools companies is expected to rebound in 2023, finishing the year at around $8 billion to $9 billion. This sector includes companies developing advanced diagnostics tools, medical imaging technologies, and remote patient monitoring solutions.

Healthtech

While late-stage investments in healthtech may slow down in 2023, the overall outlook for this sector remains positive. Healthtech encompasses a wide range of technologies, such as telehealth platforms, telemedicine apps, remote patient monitoring solutions, and digital health platforms. The shift towards digital health solutions and the increasing integration of technology into healthcare delivery are driving investments in this area.

Cancer Care, Mental Health, Neurology, and Primary Care

VCs have identified cancer care, mental health, neurology, and primary care as promising clinical startup sectors. These areas present significant unmet needs and opportunities for tech-enabled care innovations. For example, oncology care can be brought into patients' homes, making the experience more seamless and convenient.

AI and Machine Learning

The potential of AI and machine learning to transform healthcare is attracting VC investments. Applications include artificial intelligence for detecting and alerting stroke teams, mental health benefits platforms that triage employees to the right level of care, and remote patient monitoring for neurology patients.

The demand for healthcare services is expected to increase due to factors such as an aging population and rising healthcare needs. VCs are likely to continue investing in companies that introduce innovative care delivery models, leverage technology advancements, and enhance patient experiences.

Biotechnology

Biotechnology companies leverage biological processes and living organisms to develop innovative therapies, diagnostic tools, and research solutions. VC firms are attracted to the potential for groundbreaking discoveries, addressing unmet medical needs, and prospects for substantial returns on investment.

In summary, while VC investments in healthcare may experience a slight slowdown in the short term, the long-term outlook remains positive. VCs will continue to play a pivotal role in driving innovation, providing critical funding, and supporting early-stage healthcare companies in bringing their visions to life.

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Fintech

VCs are still cautiously optimistic about the fintech sector, and there are several sub-sectors that are particularly promising for investment in the coming years. These include:

  • Lending: With rising interest rates, companies are likely to be incentivized to act sooner rather than later to take advantage of higher interest on their cash.
  • Treasury/Deposits: Similar to lending, companies offering high-interest business accounts will be attractive to businesses looking to make the most of their idle cash.
  • CFO Stack: Software at the intersection of the CFO and CTO, which can increase revenue opportunities or manage a company's spend, is expected to be an area of interest for VCs.
  • Fintech Infrastructure: The collapse of Silicon Valley Bank highlighted the need for a more liquid marketplace for assets and deposits in the banking sector.
  • Finance Tech for Underserved Industries: There are "forgotten industries" that haven't been well-served by fintech innovation, including supply chain logistics, insurance, and manufacturing. These sectors often still rely on archaic billing systems and outdated legacy systems.

Some of the top VC firms investing in fintech include:

  • Andreessen Horowitz (a16z)
  • Sequoia Capital
  • Greylock Partners
  • Lightspeed Venture Partners
  • Bessemer Venture Partners
  • First Round
  • Accel
  • RRE Ventures
  • TTV Capital
  • Index Ventures
  • Valar Ventures
  • Founders Fund
  • Kleiner Perkins
  • Bain Capital Ventures (BCV)
  • Global Founders Capital (GFC)
  • Fin Capital
  • CFV Ventures
  • Illuminate Financial
  • Ribbit Capital
  • Better Tomorrow Ventures (BTV)
  • SV Angel
  • Fenway Summer
  • Nyca Partners
  • Clocktower Technology Ventures
  • General Catalyst
  • Social Capital
  • Slow Ventures
  • Digital Currency Group (DCG)
  • Alumni Ventures
  • Torch Capital
  • SignalFire
  • PS27 Ventures
  • The Artemis Fund
  • Secocha Ventures
  • Precursor Ventures
  • Collaborative
  • FinTech Collective

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Sustainability

  • Clean energy and net zero emissions: The transition from fossil fuels to renewable energy sources such as solar, wind and geothermal power is central to sustainability strategies. As countries increase their use of clean energy, companies are investing in renewable energy projects and implementing energy-efficient technologies and practices.
  • Sustainable supply chains: More businesses are looking to make their supply chain operations more sustainable by using eco-friendly packaging and production materials, reducing waste, and ensuring fair labour practices and safe work environments.
  • Sustainability reporting: The European Union's Corporate Sustainability Reporting Directive, which requires companies to make annual reports on the environmental and social impact of their activities, came into effect in January 2024. Companies are also facing pressure from investors, regulators and stakeholders to disclose their exposure to climate-related risks.
  • The circular economy: The circular economy model, which minimises waste and maximises the use of resources, is expected to generate USD 4.5 trillion in economic benefits by 2030. Businesses play a crucial role by redesigning products to be more durable, reusable or recyclable, and by cutting down on resource consumption and waste throughout the product life cycle.
  • Biodiversity: Efforts to preserve biodiversity and natural resources gained momentum in 2022 when countries signed a global biodiversity framework at the United Nations' COP15 summit. The "nature-positive" movement aims to stop, avoid and reverse environmental destruction.
  • Sustainable technology: With advances in artificial intelligence (AI), machine learning (ML) and other technologies, 2024 is set to be a big year for tech-driven sustainability. AI can help optimise energy consumption, reduce emissions and support decision-making processes in sustainability strategy development.
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Diversity and Inclusion

Venture capital (VC) investors are increasingly recognising the importance of diversity and inclusion in their industry. Organisations such as Diversity VC are working towards a fairer and more diverse VC industry, aiming to provide venture funds with the tools and resources to promote diversity and inclusion in their firms and the companies they fund.

Diversity VC has a community of over 100 funds worldwide committed to increasing diversity and inclusion in the VC ecosystem. They also offer an internship program, Future VC, which provides on-the-job experience and a support network for underrepresented talent in the industry.

In addition, Diversity VC sponsors events such as SuperVenture, a networking and learning event for senior LPs and VCs, and the Diverse Venture Capital Emerging Managers Conference, which brings together the diverse emerging venture capitalist ecosystem to build a stronger community and discuss trends, challenges, and opportunities.

The topic of diversity and inclusion in VC is also gaining traction through reports and toolkits. Diversity VC has released a toolkit for building inclusive founder engagement strategies, and an in-depth report on diversity in US venture-backed startups. They also work with venture capital funds to assess and improve their DEI metrics.

With a focus on diversity and inclusion, the VC industry can strive towards better decision-making, higher returns, and a future that represents the rich tapestry of society.

Frequently asked questions

VCs will continue to invest in technology, healthcare, and consumer products and services, but the focus will become more granular. There will also be a growing interest in sustainability, clean energy, and other green technologies, as well as fintech, blockchain, and companies promoting diversity and inclusion.

VC investment trends are shaped by technological advancements, shifting demographics, changes in consumer behaviour, and economic conditions such as inflation, interest rates, and bank failures.

VCs need to be cautious about deploying capital due to recent macroeconomic factors such as high inflation and market volatility. They also face challenges when assessing potential investments as most new companies fail, and it can be difficult to predict which will succeed.

Startups should focus on demonstrating strong leadership, having a compelling customer-centric solution, and addressing a large addressable market. They should also consider the timing of their investment pitch, as VC interest can be influenced by broader macroeconomic and cultural trends.

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